The nexgenpts utilizes lal reagents in an fdalicensed disposable test cartridge with a handheld reader for a completely contained, realtime endotoxin testing system. The tecan sunrise with endoscan v software12 is an example of an incubating microplate reader with software designed to collect, process, and store data using protocols for lal endotoxin measurement. Sep 09, 2019 charles river laboratories international, inc. An updated endoscan v software platform for endotoxin detection and measurement, and the introduction of the celsis automated detection solution for rapid sterility to ensure continued product quality and contamination control for pharmaceutical manufacturing clients. No other brand of endotoxin testing instruments is equipped to use cartridge technology.
Five frequently asked questions about data integrity, risk mitigation and human error in endotoxin testing. The endosafemcs is a multicartridge system that utilizes fdalicensed disposable cartridges for accurate, convenient endotoxin testing. The mcs is a benchtop test system that runs with your pc and endoscanvtm, charles river s endotoxinmeasuring software. Endosafe nexgenmcs, a rapid multicartridge instrument. Charles river laboratories provide the most comprehensive, integrated portfolio of drug development products and services available from a single global provider, spanning the continuum from early research to the support of marketed products. Microtrend can be tailored to meet a range of objectives. With random access, you can run your samples as needed and not wait for a full batch of samples for testing. Charles rivers portfolio management capabilities allow investment managers to view exposures and holdings, understand the impact of asset allocation and derisking decisions, and construct portfolios that align with investment mandates. It provides an integrated solution to securely consolidate, query, and analyze all realtime endotoxin data for necessary internal qa and regulatory authorities trending reports, effortlessly elevating compliance status. Sep 12, 2019 charles river laboratories has launched two new products in its microbial solutions portfolio including an update to its endosafe endoscanv software, which, when combined with the companys endosafe instruments and reagents, provides a complete endotoxin detection system, said julie sperry, senior director, microbial solutions product. Crl today announced the launch of two new products in its microbial solutions portfolio. Endosafe nexgenmcs endosafe nexus only charles river endosafe instruments use cartridge technology.
Our two kinetic turbidimetric lal reagents, kta and kta2, yield quantitative endotoxin values when used with a microplate equipped with endotoxinmeasuring software. Endosafe nexgenpts, a rapid pointofuse spectrophotometer. Charles rivers endoscanv is a validated endotoxin detection and measurement software used to generate and report quantitative test data. Ideal for highvolume water testing or samples that require dilutions, the system utilizes proven innovative lal cartridge technology a stateoftheart liquid handling system and simple data management software to test 48 to 60 samples with minimal preparation and supervision. Charles river laboratories has announced the launch of two new products in its microbial solutions portfolio. Both the endosafe endoscanv and charles river cortex software are methods for performing an endotoxin analysis. Endosafe nexus charles river laboratories singapore. Charles river is pleased to introduce the first fully automated robotic system developed specifically for highvolume endotoxin testing in the central qc lab. Charles river laboratories updates microbial solutions portfolio. Sep 10, 2019 charles rivers endoscanv is a validated endotoxin detection and measurement software used to generate and report quantitative test data.
The instrument can be used to detect endotoxin levels as low as 0. The software has been verified and validated to be consistent with fda requirements and performs the requisite calculations and reports. Sep 09, 2019 charles rivers endoscanv is a validated endotoxin detection and measurement software used to generate and report quantitative test data. The elx808 absorbance microplate reader offers proven performance for many applications, from endpoint to fast kinetic protocols. Charles river laboratories international has launched two new products in its microbial solutions portfolio. Founded in 1947 in boston, massachusetts, charles river is now one of the worlds most recognised drug research and development companies.
The endosafepts is a handheld spectrophotometer that utilizes fdalicensed disposable cartridges for accurate, convenient endotoxin testing. Page 18 endosafe portable test system users guide 5. Catalogs and flyers charles river apparel javascript seems to be disabled in your browser. Charles river laboratories announces updates to microbial. The endosafe pts portable test system users guide version 7 1023 wappoo road suite 43b, charleston, sc 29407 phone. Charles river optio wggps2 operating manual pdf download. Charles river cortex an allencompassing endotoxin software platform for data and instrument management, investigation analysis, and process monitoring. Automated endotoxin measurement systems designed as tube readers are available for kineticcolorimetric measurement. It has been verified and validated to be consistent with fda requirements and performs requisite calculations and. The elx808 is widely recognized as offering the industryleading 4zone temperature control, which optimizes conditions for even the most temperature sensitive assays. Yes, there are two other charles river endosafe endotoxin testing instruments that can be used with the endosafe lal cartridge technology. Sep 10, 2019 charles river laboratories has announced the launch of two new products in its microbial solutions portfolio. Endosafepts from charles river laboratories selectscience.
Upon successful installation and registration of the software select ptsmcs as the reader type from the reader options dialog box. Downloading output to pc using the pts logger software. Endosafe ptsmcs cartridges endoscanv, is endotoxin measuring software that is compatible with a variety of plate readers. A ceramic hydroxyapatite based purification platform. With test results in just 15 minutes, you can rapidly move forward with your study or the next step in your process. The tecan sunrise with endoscanv software12 is an example of an incubating microplate reader with software designed to collect, process, and store data using protocols for lal endotoxin measurement. Explore bacterial endotoxin testing from charles river. Endosafe mcs in bengaluru, charles river laboratories india. Rapid microbial detection systems market 2020 analysis by. List of all current catalogs available to view online, download, or order a hardcopy. Endoscanv, an endotoxin measuring software that is compatible with a variety of plate readers. Endosafe endoscanv is the only endotoxin testing software that is compatible with the charles river endosafe cartridge instruments utilizing the proprietary cartridge technology. The charles river endosafe nexgenmcs is a revolutionary rapid endotoxin detection system that utilizes an fdalicensed lal testing cartridge along with a multicartridge spectrophotometer to provide endotoxin test results for up to 5 samples in about 15 minutes.
Charles river laboratories updates microbial solutions. Accurate, intuitive data analysis is an important part of a kinetic endotoxin detection program. Sep 10, 2019 charles river laboratories international has launched two new products in its microbial solutions portfolio. Microtrend effectively leverages the power of structured query language sql to provide a comprehensive trending tool that tracks and trends lal test data. Conquering data integrity by eliminating human error. Endosafe nexgenpts endotoxin testing charels river. Ideal for highvolume water testing or samples that require dilutions, the nexus tests 48 to 60 samples per run with minimal preparation and supervision. Charles river offers two software packages designed to increase the efficiency and the compliance of the testing program in your lab. Both reagents are buffered to provide significant interferenceresistance properties and are fdalicensed for use in product release testing. The decentralized, multiclient solution provides complete qaqc instrument oversight. Endosafe mcs in bengaluru, charles river laboratories. Endosafe nexgenmcs from charles river description the endosafemcs is a multicartridge endotoxin detection system that utilizes fdalicensed endosafepts cartridges for fast, quantitative and accurate endotoxin results. Charles river s endoscanv is a validated endotoxin detection and measurement software used to generate and report quantitative test data. An updated endoscanv software platform for endotoxin detection and measurement, and the introduction of the celsis automated detection solution for rapid sterility to ensure continued product quality and contamination control for pharmaceutical manufacturing clients.
This benchtop test system can test up to five samples in about fifteen minutes. The software performs the requisite measurements, calculations, and creates test reports with the convenience of digital signature report approval. Charles river laboratories, france and observed at 340 nm with an onset optical density value set at 0. Charles river s endoscan v is a validated endotoxin detection and measurement software used to generate and report quantitative test data. Detailed reports can be generated from the nexgenmcs through endoscanv version 5.
The mcs is a benchtop test system that runs with your pc and endoscanvtm, charles rivers endotoxinmeasuring software. Tracks and trends results using endoscanv software. Charles river laboratories has launched two new products in its microbial solutions portfolio including an update to its endosafe endoscanv software, which, when combined with the companys endosafe instruments and reagents, provides a complete endotoxin detection system, said julie sperry, senior director, microbial solutions product management and strategic marketing, charles. Plates were analysed using a biotek elx808 absorbance microplate reader with endoscanv software version 4. The pts is so easytouse, you can run the test in just three simple steps. Cortex software for endotoxin analysis charles river. This will show all available bays for each instrument connected. The company has a number of endotoxin detection and microbial testing products on the market, including the portable handheld endosafepts and the multicartridge endosafemcs and charles river is now pioneering the endosafenexus, a fully.
Using endoscanv with endosafe pts for data acquisition. Charles river cortex provides an integrated solution to securely consolidate, query, and analyze all realtime endotoxin data for necessary internal qa and fda trending reports. The charles river cortex software also enables you to continuously monitor your endotoxin results through custom alerts to address issues immediately. It has been verified and validated to be consistent with fda requirements and performs requisite calculations and batch reports for product release. View online or download charles river endosafepts operating manual.
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